BACKGROUND General-purpose large language models (LLMs) are increasingly being tested in mental health care, where language is central to assessment, diagnosis, risk evaluation, therapeutic interaction, monitoring, and patient education. However, their clinical usefulness, safety, and readiness for implementation remain uncertain. Existing reviews have largely been descriptive or scoping in nature, and broad health care reviews have not examined in detail the distinctive risks and applications of LLMs in mental health care. OBJECTIVE We aim to systematically review empirical evidence
A large-scale ECG foundation model trained on more than 1.7 million ECGs paired with clinician reports consistently outperformed supervised and non-ECG foundation models across cardiovascular diagnosis and prediction tasks. The model, called ECG-C...
Use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) was consistently associated with a lower risk of tuberculosis (TB) in patients with type 2 diabetes (T2D) compared with 4 other commonly prescribed glucose-lowering agents, according to a la...