Therapeuti

Therapeutic-dose heparin more likely to benefit those with less severe COVID-19 at hospitalisation, lower BMI

The benefits and harms of therapeutic-dose heparin for hospitalised patients with COVID-19 varied by patient characteristics, illustrating the importance of considering heterogeneity of treatment effect (HTE) in the design and analysis of randomised clinical trials, according to a study published in JAMA. An exploratory analysis of a multiplatform randomised trial of therapeutic-dose heparin for early-pandemic patients with moderate (n = 2,218) or severe (n = 1,102) COVID-19 found that in all 3 approaches for testing HTE (conventional subgroup analysis, risk-based analysis, and effect-based...

Pandemic stress had a greater impact on those who were pregnant, study finds

COVID-19-related stress had a greater impact on the mental health of those who were pregnant during the pandemic, compared with those who weren’t, according to a study published in JAMA Network Open. “The COVID-19 pandemic has exacerbated existing...

New Treatment Can Improve Cardiac Pump Function in Patients With Heart Failure

The hunger hormone ghrelin can increase the heart’s pump capacity in patients with heart failure, according to a study published in the European Heart Journal. “Heart failure is the most common cause of hospitalisation in older generations and is ...


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Can Patien
3:56

Can Patients with Hypertrophic Cardiomyopathy do Vigorous Exercise? - A Multinational Lifestyle And Exercise Study

Presenter: Rachel Lampert
Cardiology
ACC 2023
Efficacy a
3:31

Efficacy and Safety of Oral PCSK9 Inhibitor, MK-0616 in the Treatment of Hypercholesterolemia

Presenter: Eliot A. Brinton
Cardiology
ACC 2023
Transcathe
4:33

Transcatheter Edge-to-Edge Repair of Functional Mitral Regurgitation in Heart Failure - The COAPT Trial

Presenter: Gregg Stone
Cardiology
ACC 2023
Elevated L
16:07

Elevated Lipoprotein(a) as a Risk Enhancing Factor for Atherosclerotic Cardiovascular Disease

Presenter: Nathan D. Wong
Cardiology
ACC 2023
Sotatercep...
8:26

Sotatercept in combination with background therapy for the treatment Of Pulmonary Arterial Hypertension — STELLAR Trial

Presenter: Marius Hoeper
Cardiology
ACC 2023
The Omega-
6:27

The Omega-3 Mystery: New Evidence Supports the Therapeutic Value of EPA

Presenter: Eliot A. Brinton
Cardiology
ACC 2023
Post neoad
20:22

Post neoadjuvant therapy in Triple Negative Breast Cancer

Presenter: Hope Rugo
Oncology : Breast Cancer
SABCS 2022
Treatment
13:12

Treatment options for early, HR+, HER2- Breast Cancer

Presenter: Hope Rugo
Oncology : Breast Cancer
SABCS 2022
LMWH use i
6:49

LMWH use in pregnancy: The Highlow and the ALPINE trial

Presenter: Saskia Middeldorp
Hematology
ASH 2022
Highlights
4:57

Highlights of the San Antonio Breast Cancer Symposium 2022

Oncology : Breast Cancer
SABCS 2022
Targeting
9:22

Targeting CV risk factors with GLP-1 RAs in people with obesity

Presenter: A. Michael Lincoff
Diabetology
EASD 2022
Once weekl
7:36

Once weekly insulin: The ONWARDS 2 study

Presenter: Tina Vilsbøll
Diabetology
EASD 2022
Is HFpEF h
20:42

Is HFpEF hiding in your practice? Key messages of the DELIVER study: Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction

Presenter: Silvio Inzucchi
Diabetology
EASD 2022
Semaglutid
10:59

Semaglutide 2.4 mg reduces the 10-year type 2 diabetes risk in people with overweight or obesity

Presenter: Timothy Garvey
Diabetology
EASD 2022
Semaglutid
7:29

Semaglutide 2.4 mg improved glucose metabolism and reverted prediabetes to normoglycaemia in adults with overweight or obesity vs liraglutide 3.0 mg

Diabetology
EASD 2022
Primary re
5:15

Primary results of the phase 3 KEYNOTE-412 study

Presenter: Jean-Pascal Machiels
Oncology
ESMO 2022
Carfilzomi
6:49

Carfilzomib, Dexamethasone, and Daratumumab Versus Carfilzomib and Dexamethasone for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma (RRMM): Primary Analysis Results from the Randomized, Open-Label, Phase 3 Study Candor

Presenter: Saad Z. Usmani
Hematology
Inhibition
6:22

Inhibition of Complement C1s with Sutimlimab in Patients with Cold Agglutinin Disease: Results from the Phase 3 Cardinal Study

Presenter: Alexander Röth
Hematology
The QUAZAR
8:20

The QUAZAR AML-001 Maintenance Trial: Results of a Phase III International, Randomized, Double-Blind, Placebo-Controlled Study of CC-486 (Oral Formulation of Azacitidine) in Patients with Acute Myeloid Leukemia in First Remission

Presenter: Andrew H. Wei
Hematology
Validation
7:11

Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing

Presenter: David A. Williams
Hematology
A Randomiz
4:40

A Randomized Phase 3 Trial of Blinatumomab Vs. Chemotherapy As Post-Reinduction Therapy in High and Intermediate Risk First Relapse of B-ALL in Children and Adolescents/Young Adults Demonstrates Superior Efficacy and Tolerability of Blinatumomab

Presenter: Patrick A. Brown
Hematology
CLARIFY -
7:07

CLARIFY - In stable coronary disease, patients with angina and prior myocardial infarction have a poor prognosis despite adherence to guideline recommanded therapies. Final 5-year results from the CLARIFY study

Presenter: Emmanuel Sorbets
Cardiology
SWEDEHEART
5:26

SWEDEHEART: Secondary prevention medication after coronary artery bypass surgery and long-term mortality: A longitudinal population-based study from the SWEDEHEART registry

Presenter: Erik Bjoerklund
Cardiology
ICD use in
4:31

ICD use in HF - Association between implantable cardioverter-defibrillator use for primary prevention and mortality: a prospective propensity-score matched study

Presenter: Benedikt Schrange
Cardiology
PURE: Impa
10:51

PURE: Impact of modifiable risk factors on cardiovascular disease and mortality

Presenter: Salim Yusuf
Cardiology
RAPIDTnT:
5:37

RAPIDTnT: A randomised trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T

Presenter: Derek Chew
Cardiology
ENTRUST-AF
7:45

ENTRUST-AF PCI - Edoxaban-based versus vitamin-K-antagonist-based anti-thrombotic regimen following successful coronary stenting in atrial fibrillation patients

Presenter: Andreas Goette
Cardiology
POPular Ge
6:51

POPular Genetics - Genotype-guided oral P2Y12-inhibition in patients with St-segment elevation myocardial infarction undergoing primary PCI : a randomized, open-label, multicenter trial

Presenter: Jurrien M. Ten Berg
Cardiology
Combined e
5:03

Combined effect of lower LDL-C and lower SBP on the lifetime risk od cardiovascular disease

Presenter: Brian A. Ference
Cardiology
AFIRE - Ri
4:47

AFIRE - Rivaroxaban monotherapy versus dual therapy in patients with atrial fibrillation and stable coronary artery disease

Presenter: Satoshi Yasuda
Cardiology
GALACTIC -
7:23

GALACTIC - Goal-directed AfterLoad Reduction in Acute Congestive Cardiac Decompensation: a randomized controlled trial

Presenter: Christian Eugen Mueller
Cardiology
Salt subst
5:16

Salt substitution and community-wide reduction in blood pressure and hypertension incidence

Presenter: J. Jaime Miranda
Cardiology
Long-term
8:46

Long-term efficacy and safety of ixekizumab

Presenter: Andrew Blauvelt
Dermatology
Paradigm s
12:05

Paradigm shift in the early NSCLC? The role of ICIs in the adjuvant treatment

Presenter: Federico Cappuzzo
Oncology
How will t
9:43

How will the current therapeutic options change the treatment of RCC in the daily practice?

Presenter: Camillo Porta
Oncology
The role o
5:58

The role of immune checkpoint inhibitors and VEGF TKIs in the adjuvant treatment of renal cell carcinoma

Presenter: David F. McDermott
Oncology
Treatment
11:50

Treatment intensification in the treatment of prostate cancer

Presenter: Oliver Sartor
Oncology
Pembrolizu
16:35

Pembrolizumab as post nephrectomy adjuvant therapy for patients with renal cell carcinoma

Presenter: Stefan N. Symeonides
Oncology
State of t
6:13

State of the art treatment of bladder cancer

Presenter: Matthew R. Zibelman
Oncology
First-line
7:41

First-line pembrolizumab plus chemotherapy versus chemotherapy in advanced esophageal cancer

Presenter: Ken Kato
Oncology
Treatment
3:27

Treatment of iron deficiency in acute and chronic heart failure

Presenter: Piotr Ponikowski
Cardiology
Alcohol se
6:32

Alcohol septal ablation in hypertrophic cardiomyopathy: past and future

Presenter: Hubert Seggewiss
Cardiology
The use of
3:35

The use of SGLT2 inhibitors in the prevention and treatment of heart failure

Presenter: Petar M. Seferovic
Cardiology
Direct myo
5:15

Direct myosin inhibitors in hypertrophic cardiomyopathy: a new era?

Presenter: Iacopo Olivotto
Cardiology
Diagnostic
10:55

Diagnostic delay in pulmonary arterial hypertension

Presenter: Barbro Kjellström and Bodil Ivarsson
Clinical I
6:21

Clinical Impact of Liraglutide as a Treatment of Obesity

Presenter: Babak Dehestani
Internal Medicine
Associatio
20:17

Association of GLP 1 Analogs and Agonists Administered for Obesity with Weight Loss and Adverse Events

Presenter: Michael Camilleri
Internal Medicine
Liraglutid
13:26

Liraglutide for Weight Management in the Real World

Presenter: Roman Vangoitsenhoven
Cardiology , Diabetology