Urinary metabolomics provide insights into coronary artery disease in individuals with type 1 diabetes.
BACKGROUND Type 1 diabetes increases the risk of coronary artery disease (CAD). High-throughput metabolomics may be utilized to identify metabolites associated with disease, thus, providing insight into disease pathophysiology, and serving as predictive markers in clinical practice. Urine is less tightly regulated than blood, and therefore, may enable earlier discovery of disease-associated markers. We studied urine metabolomics in relation to incident CAD in individuals with type 1 diabetes. METHODS We prospectively studied CAD in 2501 adults with type 1 diabetes from the Finnish Dia...
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